Details for gene set NCI_TNF RECEPTOR SIGNALING PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	set02_ATM_minus_versus_BT_ATM_minus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_TNF RECEPTOR SIGNALING PATHWAY
Enrichment Score (ES)	-0.44525537
Normalized Enrichment Score (NES)	-2.0409615
Nominal p-value	0.0
FDR q-value	0.02856077
FWER p-Value	0.053

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL2RA	15	4.747	0.0118	No
2	NUP214	64	3.714	0.0193	No
3	RPS6KA5	107	3.380	0.0263	No
4	CREB1	126	3.257	0.0340	No
5	LCK	137	3.203	0.0419	No
6	MAP2K6	175	2.990	0.0481	No
7	ITCH	197	2.938	0.0548	No
8	CSNK2A1	381	2.459	0.0529	No
9	PRKCA	397	2.430	0.0586	No
10	CASP3	413	2.406	0.0642	No
11	ATF2	444	2.361	0.0690	No
12	MAP3K7	448	2.353	0.0750	No
13	CREBBP	519	2.250	0.0777	No
14	YWHAZ	622	2.135	0.0786	No
15	IL5	751	2.009	0.0780	No
16	GSK3B	765	1.997	0.0827	No
17	PIK3CA	824	1.937	0.0851	No
18	PLA2G4A	906	1.879	0.0863	No
19	HBP1	986	1.830	0.0874	No
20	EIF4E	1119	1.747	0.0860	No
21	CTLA4	1130	1.742	0.0901	No
22	MAPK8	1169	1.724	0.0928	No
23	MAP3K7IP1	1279	1.667	0.0922	No
24	CAMK4	1351	1.628	0.0932	No
25	SYK	1418	1.598	0.0944	No
26	GZMB	1463	1.577	0.0965	No
27	RAB5A	1531	1.549	0.0975	No
28	YWHAE	1550	1.540	0.1007	No
29	MAPK1	1594	1.523	0.1027	No
30	TRAF6	1621	1.510	0.1055	No
31	CSNK1A1	1654	1.498	0.1079	No
32	ESR1	1688	1.488	0.1103	No
33	PPARGC1A	1723	1.472	0.1126	No
34	CFL2	1742	1.467	0.1156	No
35	MITF	2097	1.330	0.1028	No
36	PIK3R1	2157	1.312	0.1035	No
37	CDC25B	2332	1.248	0.0988	No
38	PTPRK	2458	1.209	0.0962	No
39	PRKCE	2610	1.173	0.0923	No
40	POU2F1	2833	1.121	0.0851	No
41	ADAM17	2843	1.120	0.0876	No
42	TOP1	3099	1.061	0.0786	No
43	MAP4K5	3156	1.048	0.0788	No
44	RAN	3501	0.968	0.0655	No
45	IGF1	3560	0.957	0.0653	No
46	CEBPB	3658	0.937	0.0633	No
47	PIM1	3908	0.888	0.0542	No
48	ERC1	3923	0.885	0.0558	No
49	MEF2A	3968	0.878	0.0561	No
50	SATB1	3979	0.876	0.0580	No
51	MALT1	4026	0.868	0.0581	No
52	PAK3	4071	0.860	0.0584	No
53	CRADD	4268	0.828	0.0515	No
54	KPNB1	4321	0.818	0.0513	No
55	MAP3K7IP2	4322	0.818	0.0534	No
56	TH	4459	0.792	0.0492	No
57	BAD	4507	0.786	0.0491	No
58	AKT1	4977	0.711	0.0294	No
59	UBE2D3	4979	0.711	0.0312	No
60	EP300	5873	0.578	-0.0084	No
61	FASLG	5895	0.575	-0.0079	No
62	NFATC3	5945	0.567	-0.0087	No
63	RALA	5982	0.562	-0.0088	No
64	IL4	5986	0.560	-0.0075	No
65	CHUK	6349	0.506	-0.0229	No
66	PDGFA	6424	0.496	-0.0250	No
67	BAX	6537	0.482	-0.0289	No
68	ASAH1	7016	0.418	-0.0498	No
69	E2F1	7467	0.357	-0.0696	No
70	CYCS	7517	0.351	-0.0709	No
71	XPO1	7628	0.335	-0.0751	No
72	CDK4	7918	0.298	-0.0877	No
73	FKBP8	8018	0.285	-0.0915	No
74	TNIK	8345	0.240	-0.1059	No
75	PPARG	8381	0.235	-0.1069	No
76	FGR	8504	0.217	-0.1119	No
77	LRDD	8832	0.171	-0.1265	No
78	MAP3K1	8906	0.161	-0.1295	No
79	ATF1	9205	0.120	-0.1429	No
80	TNFRSF1A	9263	0.111	-0.1452	No
81	DIABLO	9521	0.071	-0.1569	No
82	IL3	9524	0.071	-0.1568	No
83	CAV1	9719	0.041	-0.1656	No
84	CTSD	9890	0.014	-0.1734	No
85	CALM2	10266	-0.045	-0.1906	No
86	EGR4	10291	-0.048	-0.1916	No
87	APAF1	10407	-0.066	-0.1967	No
88	LMNB1	10486	-0.076	-0.2001	No
89	CASP1	10532	-0.083	-0.2019	No
90	EGF	10831	-0.129	-0.2153	No
91	AKAP5	10935	-0.146	-0.2197	No
92	MAP4K3	11157	-0.175	-0.2294	No
93	RAF1	11386	-0.204	-0.2394	No
94	NSMAF	12010	-0.274	-0.2674	No
95	PAK2	12116	-0.285	-0.2715	No
96	TRAF2	12318	-0.311	-0.2799	No
97	LMNB2	12514	-0.335	-0.2880	No
98	DDIT3	12521	-0.335	-0.2874	No
99	SMPD2	12612	-0.346	-0.2906	No
100	TBX21	12958	-0.386	-0.3055	No
101	BLK	13045	-0.396	-0.3085	No
102	MAP3K8	13234	-0.417	-0.3160	No
103	PRKCI	13268	-0.420	-0.3164	No
104	MAP2K3	13472	-0.447	-0.3246	No
105	DUSP16	13526	-0.454	-0.3259	No
106	SMPD1	13543	-0.455	-0.3254	No
107	SRC	13765	-0.482	-0.3343	No
108	ELK4	13831	-0.491	-0.3360	No
109	USF1	13855	-0.493	-0.3358	No
110	CCM2	13964	-0.505	-0.3394	No
111	BIRC2	14071	-0.516	-0.3430	No
112	TRADD	14236	-0.537	-0.3491	No
113	RNF128	14244	-0.538	-0.3480	No
114	CSF2	14405	-0.557	-0.3539	No
115	REL	14487	-0.568	-0.3562	No
116	SPHK2	14517	-0.572	-0.3560	No
117	YES1	14598	-0.581	-0.3582	No
118	MAP2K4	14640	-0.588	-0.3585	No
119	HSPB1	15001	-0.628	-0.3735	No
120	YWHAQ	15062	-0.634	-0.3746	No
121	CALM1	15082	-0.637	-0.3738	No
122	IFNG	15303	-0.665	-0.3821	No
123	MAPK3	15401	-0.677	-0.3848	No
124	RIPK2	15580	-0.698	-0.3912	No
125	SMPD3	15637	-0.706	-0.3919	No
126	TSC2	15645	-0.708	-0.3904	No
127	PAWR	15663	-0.710	-0.3893	No
128	EIF4EBP1	15826	-0.732	-0.3949	No
129	MAP2K2	16032	-0.762	-0.4023	No
130	FADD	16038	-0.763	-0.4005	No
131	CASP8	16284	-0.795	-0.4097	No
132	FOSL1	16325	-0.800	-0.4095	No
133	CD40LG	16375	-0.807	-0.4096	No
134	MAPKAPK2	16390	-0.809	-0.4081	No
135	NFKBIA	16391	-0.809	-0.4060	No
136	HCK	16436	-0.815	-0.4059	No
137	YWHAB	16464	-0.818	-0.4050	No
138	SLC9A1	16483	-0.821	-0.4037	No
139	PAK1	16504	-0.823	-0.4024	No
140	SREBF1	16535	-0.827	-0.4016	No
141	DUSP8	16645	-0.841	-0.4044	No
142	NRK	16693	-0.847	-0.4044	No
143	MAP3K14	16757	-0.855	-0.4050	No
144	RIPK1	16874	-0.871	-0.4081	No
145	CASP4	16907	-0.877	-0.4073	No
146	PTGS2	17046	-0.900	-0.4113	No
147	GATA3	17055	-0.902	-0.4093	No
148	BIRC3	17339	-0.944	-0.4198	No
149	RFFL	17380	-0.950	-0.4192	No
150	MAPK9	17448	-0.962	-0.4197	No
151	ETV1	17507	-0.973	-0.4198	No
152	RELA	17566	-0.984	-0.4199	No
153	PRKACA	17631	-0.996	-0.4203	No
154	YWHAH	17687	-1.006	-0.4202	No
155	PRKRA	17878	-1.038	-0.4262	No
156	BID	17883	-1.039	-0.4236	No
157	DFFA	17956	-1.052	-0.4242	No
158	GNB2L1	17975	-1.053	-0.4223	No
159	PARP1	18005	-1.059	-0.4208	No
160	DGKA	18084	-1.073	-0.4216	No
161	JUN	18099	-1.076	-0.4194	No
162	RPS6KA4	18117	-1.078	-0.4174	No
163	CASP2	18290	-1.111	-0.4224	No
164	MKNK1	18366	-1.127	-0.4229	No
165	BCL2	18625	-1.179	-0.4317	No
166	ATM	18685	-1.190	-0.4313	No
167	IKBKG	18928	-1.246	-0.4391	No
168	CYLD	18965	-1.255	-0.4375	No
169	GAS2	19048	-1.271	-0.4379	No
170	CASP9	19125	-1.289	-0.4380	No
171	DFFB	19145	-1.295	-0.4355	No
172	PRKCQ	19298	-1.339	-0.4390	No
173	TNF	19341	-1.351	-0.4374	No
174	RAC1	19377	-1.360	-0.4354	No
175	CALM3	19591	-1.421	-0.4415	Yes
176	BAG4	19659	-1.443	-0.4408	Yes
177	TP53	19687	-1.455	-0.4382	Yes
178	TNFAIP3	19726	-1.471	-0.4361	Yes
179	PTK2	19751	-1.476	-0.4334	Yes
180	SQSTM1	19798	-1.497	-0.4315	Yes
181	APP	19814	-1.503	-0.4283	Yes
182	FKBP1A	19825	-1.506	-0.4248	Yes
183	MYC	19912	-1.534	-0.4247	Yes
184	KSR1	20065	-1.594	-0.4275	Yes
185	ACTA1	20070	-1.597	-0.4235	Yes
186	SFN	20083	-1.603	-0.4199	Yes
187	FYN	20107	-1.612	-0.4167	Yes
188	IKBKB	20132	-1.623	-0.4135	Yes
189	STAT1	20172	-1.640	-0.4110	Yes
190	CASP6	20177	-1.642	-0.4069	Yes
191	MEF2C	20238	-1.670	-0.4053	Yes
192	PRKCZ	20308	-1.703	-0.4040	Yes
193	SLC3A2	20423	-1.750	-0.4047	Yes
194	MAP2K1	20473	-1.779	-0.4022	Yes
195	PRKCD	20514	-1.805	-0.3993	Yes
196	SRF	20535	-1.816	-0.3955	Yes
197	LIMK1	20601	-1.848	-0.3936	Yes
198	MAF	20636	-1.867	-0.3903	Yes
199	MAP2K7	20666	-1.888	-0.3867	Yes
200	PRKG1	20704	-1.910	-0.3834	Yes
201	DUSP10	20732	-1.927	-0.3795	Yes
202	LSP1	20764	-1.943	-0.3759	Yes
203	PTPN1	20769	-1.947	-0.3709	Yes
204	RALB	20823	-1.981	-0.3682	Yes
205	MAP3K12	20842	-1.995	-0.3638	Yes
206	MEF2D	20891	-2.028	-0.3607	Yes
207	GDI1	20903	-2.033	-0.3558	Yes
208	ATF6	20914	-2.044	-0.3509	Yes
209	NFKB1	20944	-2.065	-0.3468	Yes
210	MAPKAPK5	20969	-2.083	-0.3425	Yes
211	FBXW11	20996	-2.114	-0.3381	Yes
212	NUMA1	21077	-2.170	-0.3361	Yes
213	MAPK14	21120	-2.209	-0.3322	Yes
214	DUSP1	21121	-2.210	-0.3264	Yes
215	MAP4K2	21147	-2.232	-0.3217	Yes
216	BCL10	21159	-2.247	-0.3163	Yes
217	MADD	21207	-2.298	-0.3124	Yes
218	ARRB2	21227	-2.318	-0.3072	Yes
219	FOXP3	21314	-2.435	-0.3048	Yes
220	MAPKAPK3	21325	-2.455	-0.2988	Yes
221	PRF1	21361	-2.499	-0.2939	Yes
222	ARHGDIB	21394	-2.566	-0.2886	Yes
223	JUNB	21440	-2.670	-0.2837	Yes
224	CBLB	21453	-2.694	-0.2771	Yes
225	TCF3	21468	-2.726	-0.2706	Yes
226	GSN	21499	-2.780	-0.2647	Yes
227	MAP3K3	21546	-2.891	-0.2592	Yes
228	CASP7	21563	-2.954	-0.2522	Yes
229	NFKB2	21615	-3.137	-0.2463	Yes
230	YWHAG	21678	-3.403	-0.2402	Yes
231	TRAF1	21720	-3.630	-0.2326	Yes
232	PRKCH	21736	-3.724	-0.2235	Yes
233	NFATC2	21737	-3.736	-0.2137	Yes
234	MAP4K4	21744	-3.794	-0.2040	Yes
235	RELB	21749	-3.826	-0.1941	Yes
236	MAPK11	21793	-4.191	-0.1851	Yes
237	IRF4	21795	-4.216	-0.1741	Yes
238	LMNA	21836	-4.610	-0.1638	Yes
239	TNFRSF1B	21851	-4.763	-0.1519	Yes
240	BCL3	21865	-4.977	-0.1395	Yes
241	NFATC1	21871	-5.174	-0.1261	Yes
242	VIM	21890	-5.636	-0.1121	Yes
243	FOS	21917	-6.478	-0.0963	Yes
244	NR4A1	21923	-6.633	-0.0791	Yes
245	EGR1	21942	-8.847	-0.0567	Yes
246	EGR3	21943	-9.744	-0.0311	Yes
247	EGR2	21944	-11.902	0.0001	Yes